Silviano Trino sang this week for the first time in years.
His wife, Martha, described the moment: “He heard a song and said it reminded him of his mother, and he started singing.”
Trino had not spoken much over the past three years due to lung damage, but he sang just one day after being released from Baylor St. Luke’s Medical Center—the same hospital where Trino underwent a double-lung transplant about two weeks ago.
Trino’s surgery made history: He is one of the first Texas recipients of lungs that were transplanted using the Ex Vivo Lung Perfusion (EVLP) procedure with the TransMedics Organ Care System Lung (OCS Lung) technology. The surgery was also one of the first in the country using this technology.
The OCS Lung machine is designed to keep donor lungs functioning and “breathing” in human-like conditions from the time of the donor procedure all the way to transplant surgery. The technology maintains the organ in its own physiologic state with warm blood perfusion, ventilation and a sophisticated monitoring system to continually assess the organ as it travels from donor to recipient.
This was life-changing for Trino and a groundbreaking procedure for the lung transplantation process, where organ rejection rates are high, according to cardiothoracic surgeon Gabriel Loor, surgical director of the lung transplant program at Baylor St. Luke’s Medical Center and director of lung transplantation in the Michael E. DeBakey Department of Surgery at Baylor College of Medicine, and the surgeon who led the transplant. About 50 percent of rejections are caused by the immune system, while 30 percent are due to primary graft dysfunction—an acute lung injury encountered within the first 72 hours after a transplant.
“A trial using the Ex Vivo Lung Perfusion procedure showed that it was able to reduce the rate of primary graft dysfunction by half,” Loor said. “This means that organs being transported by this machine will be able to go longer distances and be better protected.”
Trino’s new lungs were transported from the Midwest to the Texas Medical Center and kept in the OCS Lung machine for 11 hours, Loor said. Prior to coming to Baylor St. Luke’s, the Trinos, who live in Miami, had gone to four other medical centers that perform a high volume of lung transplants, but were turned away due to Silviano’s health.
“His disease process is such that his lungs would not expand, so there was inflammation and damage,” Loor explained.
The OCS Lung System was officially approved by the U.S. Food and Drug Administration on March 23, 2018.
Trino said he was not skeptical about trying something new. Not only did this technology give him back his ability to sing, but it helped him feel better than he had in years. Thirty-six hours following the surgery, he was in his room recovering; 10 days later, he was out of the hospital.
“I’ve been sick for a long time,” Trino said. “I’m now doing things I didn’t realize I could do again.”
Baylor St. Luke’s has performed two other successful lung transplants using the technology. The surgeries were performed as part of the EXPAND II OCS trial, for which Baylor St. Luke’s is a study site, testing the outcomes of transplanted donor lungs that are transported, preserved, optimized and monitored on a portable OCS device.
Loor is the international principal investigator for the largest study in the country, evaluating the ability to increase the number of useable donor lungs using OCS technology.
Close to 100,000 people are waiting for life-saving organ donations in the U.S., according to the U.S. Department of Health and Human Services. OCS Lung technology and similar technologies mean that transplants will no longer be limited by time and location, Loor said, thus expanding the available donor pool and providing more opportunities for patients waiting for organ donations.
“This is revolutionizing the way we do transplants,” Loor said. “The Texas Medical Center is one of a handful of centers doing this. With this technology, we can’t imagine going back to the standard method of organ transport.”
RT @McGovernPulmCC: Congrats 🎊 to our Dr Alisha Young for being awarded #PhysicianOfTheYear at Memorial Hermann Cypress Hospital!#Faculty…
How can we expand the benefits of #immunotherapy to patients with autoimmune diseases? Our Dr. Patrick Hwu is finding out: https://t.co/qslSFfN3X1 #endcancer
MD Anderson Cancer CenterMDAnderson
When a small spot first appeared on her nipple, Karrie Morgan didn’t think much of it. She was shocked nearly a year later when she learned it was a symptom of Paget disease, a rare type of breast cancer that affects 4% of patients.“I thought that when it came to breast cancer, you were looking for a lump,” Karrie says. “Now I know that women should look for any change in their breasts as a possible breast cancer symptom.” #endcancerhttp://bit.ly/2S8amOm
Thank you TCH and Build a Bear, and to everyone that donates their time to put smiles on our babies💚💚💚
@KellieMorgan70 W’re so sorry to hear this, Kellie. We’re thinking of your husband.
Millennials are losing their hair faster than ever before. See what is causing this hair raising trend. https://t.co/4e9cqZiN8d #hair #hairloss
Baylor College of MedicineBaylorCollegeOfMedicine
New research into dengue and Zika viruses find shared and virus-specific mechanisms. #Zika #research
RT @DTGoteraKHOU: Medical miracles happen almost daily in Houston. 8-year old Ethan Page knows that all too well, he's able to play basebal…
@quillon3rdgrade Way to go! We appreciate your support.
U.S. Department of Veterans AffairsVeteransAffairs
Today’s #VeteranOfTheDay is Air Force Veteran Aureliano “A.J.” Salas Jr. He served from 1996 to 2018.A.J. was born in Harvey, Illinois in 1977. He graduated from Pardeeville High School in Wisconsin and went on to earn his bachelors and master’s degree from the University of Wisconsin. He completed his master’s degree in Latin American, Caribbean and Iberian studies with an emphasis in U.S. strategic policy. A.J. joined the Wisconsin Air National Guard in 1996 and served in various roles and fields such as Information Management, Counter-Drug Operations in the Caribbean and South America, Munitions Storage, Personnel Specialist and Executive Assistant to the Deputy Adjutant General. During his service, A.J. participated in numerous deployments in support of Operations Noble Eagle, Enduring Freedom, Iraq Freedom, Phantom Fury, Odyssey Dawn and Unified Protector. He also participated in humanitarian relief operations for Hurricane Felix while assigned to the US Embassy in Nicaragua.A.J.’s military awards include the Meritorious Service Medal, Air Force Commendation Medal with one Oak Leaf Cluster, Army Commendation Medal and Air Force Achievement Medal with one Oak Leaf Cluster. Additionally, he was awarded the 2006 Armed Forces Award by the League of United Latin American Citizens. In 2011, he completed his post-graduate studies at the University of Wisconsin-Madison as a Tinker-Nave Field Research Scholar. A.J. retired from the Air National Guard in 2018 as a technical sergeant.A.J. passed away on November 4, 2018 after a three-year battle with cancer.We honor his service.
Today’s #VeteranOfTheDay is Air Force Veteran Aureliano “A.J.” Salas Jr. He served from 1996 to 2018. https://t.co/kvJWUKKPcR
Shining A Light On The Gracious, Kind, And Most Helpful, Miss Katie Virola !!! She’s Been Such A Blessing To Me And My Family This Year I Can Not Thank Her Enough! She Has Made Such A Difference In Our Lives And I’ll Be Forever Grateful!! Thanks For Being You, And Always Being In My Corner!! 😄😄😄😄
RT @DankProto: ALRIGHT COOGS LET'S TEACH THEM WHOSE HOUSE THIS IS!!! https://t.co/cILKT2eCVE
@_maryssasilva We are both festive AND informative! 😸