{"id":5440,"date":"2016-01-11T17:26:56","date_gmt":"2016-01-11T17:26:56","guid":{"rendered":"https:\/\/www.tmc.edu\/news\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/"},"modified":"2019-08-16T15:01:07","modified_gmt":"2019-08-16T15:01:07","slug":"zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair","status":"publish","type":"post","link":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/","title":{"rendered":"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair"},"content":{"rendered":"<p>Heart failure is the leading cause of death worldwide, and its incidence is only increasing. A major roadblock to improving treatment is the limited proliferative capacity of the mature mammalian cardiomyocyte (CM). Recently, data from our lab and other peer labs showed that Hippo-Yap<br \/>\npathway plays crucial roles in cardiac development and cardiac repair. YAP, TEAD1 and VGLL4 are three crucial components of this pathway. Exploiting the underlying mechanism of how these three factors regulate heart growth will shed light on the cardiac regeneration drug discovery process.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Heart failure is the leading cause of death worldwide, and its incidence is only increasing. A major roadblock to improving treatment is the limited proliferative capacity of the mature mammalian cardiomyocyte (CM). Recently, data from our lab and other peer labs showed that Hippo-Yap pathway plays crucial roles in cardiac development and cardiac repair. YAP, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair - TMC News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair - TMC News\" \/>\n<meta property=\"og:description\" content=\"Heart failure is the leading cause of death worldwide, and its incidence is only increasing. A major roadblock to improving treatment is the limited proliferative capacity of the mature mammalian cardiomyocyte (CM). Recently, data from our lab and other peer labs showed that Hippo-Yap pathway plays crucial roles in cardiac development and cardiac repair. YAP, [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/\" \/>\n<meta property=\"og:site_name\" content=\"TMC News\" \/>\n<meta property=\"article:published_time\" content=\"2016-01-11T17:26:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-08-16T15:01:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2020\/01\/tmc-main-fb.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"628\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Texas Medical Center\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Texas Medical Center\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/\"},\"author\":{\"name\":\"Texas Medical Center\",\"@id\":\"https:\/\/www.tmc.edu\/news\/#\/schema\/person\/5d10b092fb6b2a2d9c11eee2507150f2\"},\"headline\":\"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair\",\"datePublished\":\"2016-01-11T17:26:56+00:00\",\"dateModified\":\"2019-08-16T15:01:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/\"},\"wordCount\":96,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/#organization\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/\",\"url\":\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/\",\"name\":\"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair - TMC News\",\"isPartOf\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/#website\"},\"datePublished\":\"2016-01-11T17:26:56+00:00\",\"dateModified\":\"2019-08-16T15:01:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.tmc.edu\/news\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.tmc.edu\/news\/#website\",\"url\":\"https:\/\/www.tmc.edu\/news\/\",\"name\":\"TMC News\",\"description\":\"Leader in Collaborative Medicine and Research\",\"publisher\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.tmc.edu\/news\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.tmc.edu\/news\/#organization\",\"name\":\"TMC News\",\"url\":\"https:\/\/www.tmc.edu\/news\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.tmc.edu\/news\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2020\/01\/TMC_News_RGB.png\",\"contentUrl\":\"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2020\/01\/TMC_News_RGB.png\",\"width\":1303,\"height\":266,\"caption\":\"TMC News\"},\"image\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.tmc.edu\/news\/#\/schema\/person\/5d10b092fb6b2a2d9c11eee2507150f2\",\"name\":\"Texas Medical Center\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.tmc.edu\/news\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/8457a8dfc36786bf9ec2a456312bd22f?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/8457a8dfc36786bf9ec2a456312bd22f?s=96&d=mm&r=g\",\"caption\":\"Texas Medical Center\"},\"url\":\"https:\/\/www.tmc.edu\/news\/author\/administrator\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair - TMC News","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/","og_locale":"en_US","og_type":"article","og_title":"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair - TMC News","og_description":"Heart failure is the leading cause of death worldwide, and its incidence is only increasing. A major roadblock to improving treatment is the limited proliferative capacity of the mature mammalian cardiomyocyte (CM). Recently, data from our lab and other peer labs showed that Hippo-Yap pathway plays crucial roles in cardiac development and cardiac repair. YAP, [&hellip;]","og_url":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/","og_site_name":"TMC News","article_published_time":"2016-01-11T17:26:56+00:00","article_modified_time":"2019-08-16T15:01:07+00:00","og_image":[{"width":1200,"height":628,"url":"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2020\/01\/tmc-main-fb.png","type":"image\/png"}],"author":"Texas Medical Center","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Texas Medical Center"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#article","isPartOf":{"@id":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/"},"author":{"name":"Texas Medical Center","@id":"https:\/\/www.tmc.edu\/news\/#\/schema\/person\/5d10b092fb6b2a2d9c11eee2507150f2"},"headline":"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair","datePublished":"2016-01-11T17:26:56+00:00","dateModified":"2019-08-16T15:01:07+00:00","mainEntityOfPage":{"@id":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/"},"wordCount":96,"commentCount":0,"publisher":{"@id":"https:\/\/www.tmc.edu\/news\/#organization"},"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/","url":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/","name":"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair - TMC News","isPartOf":{"@id":"https:\/\/www.tmc.edu\/news\/#website"},"datePublished":"2016-01-11T17:26:56+00:00","dateModified":"2019-08-16T15:01:07+00:00","breadcrumb":{"@id":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.tmc.edu\/news\/2016\/01\/zhiqiang-lin-phd-hippo-yap-pathway-in-cardiac-repair\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.tmc.edu\/news\/"},{"@type":"ListItem","position":2,"name":"Zhiqiang Lin, Ph.D.: Hippo-Yap Pathway in Cardiac Repair"}]},{"@type":"WebSite","@id":"https:\/\/www.tmc.edu\/news\/#website","url":"https:\/\/www.tmc.edu\/news\/","name":"TMC News","description":"Leader in Collaborative Medicine and Research","publisher":{"@id":"https:\/\/www.tmc.edu\/news\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.tmc.edu\/news\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.tmc.edu\/news\/#organization","name":"TMC News","url":"https:\/\/www.tmc.edu\/news\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.tmc.edu\/news\/#\/schema\/logo\/image\/","url":"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2020\/01\/TMC_News_RGB.png","contentUrl":"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2020\/01\/TMC_News_RGB.png","width":1303,"height":266,"caption":"TMC News"},"image":{"@id":"https:\/\/www.tmc.edu\/news\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.tmc.edu\/news\/#\/schema\/person\/5d10b092fb6b2a2d9c11eee2507150f2","name":"Texas Medical Center","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.tmc.edu\/news\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/8457a8dfc36786bf9ec2a456312bd22f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/8457a8dfc36786bf9ec2a456312bd22f?s=96&d=mm&r=g","caption":"Texas Medical Center"},"url":"https:\/\/www.tmc.edu\/news\/author\/administrator\/"}]}},"acf":[],"_links":{"self":[{"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/posts\/5440"}],"collection":[{"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/comments?post=5440"}],"version-history":[{"count":0,"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/posts\/5440\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/media?parent=5440"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/categories?post=5440"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tmc.edu\/news\/wp-json\/wp\/v2\/tags?post=5440"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}