{"id":32786,"date":"2020-08-09T16:29:03","date_gmt":"2020-08-09T21:29:03","guid":{"rendered":"https:\/\/www.tmc.edu\/news\/?p=32786"},"modified":"2020-08-09T19:14:36","modified_gmt":"2020-08-10T00:14:36","slug":"tmc-biodesign-expands-startup-fellowship-beyond-medical-devices-and-digital-health","status":"publish","type":"post","link":"https:\/\/www.tmc.edu\/news\/2020\/08\/tmc-biodesign-expands-startup-fellowship-beyond-medical-devices-and-digital-health\/","title":{"rendered":"TMC Biodesign expands startup fellowship beyond medical devices and digital health"},"content":{"rendered":"

Elizabeth Jaworski, Ph.D.<\/a>, who studied biochemistry and molecular biology at The University of Texas Medical Branch at Galveston<\/a>, has taken innovation from the lab bench and transformed it into a business.<\/p>\n

During her doctoral program, she worked with a professor who invented a technology for next-generation sequencing sample processing.<\/p>\n

\"\"

Elizabeth Jaworski, Ph.D., TMC Biodesign 2020-2021 Fellow<\/p><\/div>\n

\u201cI thought we should commercialize it, but at that time I didn\u2019t know much about commercializing actual products,\u201d she said.<\/p>\n

Jaworski joined Enventure<\/a>, a Houston nonprofit that helps students who are medical innovators start businesses, and realized the technology had commercial applications.<\/p>\n

\u201cWe officially incorporated the company in 2018 and we\u2019ve been developing it ever since,\u201d she said.<\/p>\n

Acting on her interest in entrepreneurship while in graduate school helped secure her slot in the new class of TMC Biodesign<\/a> Fellows at TMC Innovation<\/a> in the Texas Medical Center.<\/p>\n

Since 2015, the one-year fellowship has united innovators with diverse backgrounds who solve problems by bringing breakthrough products to market. The teams are mentored by leading experts from Texas Medical Center institutions including clinicians, experienced entrepreneurs and industry professionals.<\/p>\n

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\"\"

Jason Sakamoto, Ph.D., TMC Biodesign program strategist<\/p><\/div>\n

The one-of-a-kind program typically builds each team with medical, business and technical expertise, which is usually one physician, one\u00a0Ph.D. and one MBA.<\/p>\n

\u201cWe actually hire them as full-time employees and provide them with salaries\u00a0and benefits and we give them a substantial\u00a0discretionary fund. It\u2019s a very unique opportunity. Not many times do entrepreneurs get paid to establish their company and have access to the TMC network overall. We get a percentage of equity in the company, but it\u2019s a fantastic deal for the entrepreneurs,\u201d said Jason Sakamoto, Ph.D.<\/a>, who earned his doctorate in biomedical engineering and joined TMC Innovation in January as a biodesign program strategist. He helped make heart stents for Guidant Corp. in California as a young materials engineer and previously served as an assistant professor and co-chair in the department of nanomedicine at Houston Methodist Research Institute<\/a>.<\/p>\n

This year, COVID-19 brought an unexpected challenge for the 2020-2021 cohort: Getting started the first week of August with social distance and masks for meetings.<\/p>\n

Cardiology team added<\/strong><\/p>\n

Previously, TMC Biodesign teams have been assigned to create a medical device or digital platform.<\/p>\n

The 2020-2021 cohort of nine fellows includes a third team whose members will work on a cardiology solution with support from Baylor College of Medicine<\/a>. The interests of Jaworski\u2019s teammate, Ishan Kamat, M.D., MBA<\/a>, inspired the collaboration\u2019s timing. Tyler Melton, MBA<\/a>, rounds out the cardiology trio.<\/p>\n

As a medical student, Kamat attended a lecture (admittedly for the free food) and heard an engaging physician discuss his passion for medical device innovation in cardiothoracic surgery.<\/p>\n

\u201cHe made the field seem so accessible. I didn\u2019t even catch his name at the time,\u201d said Kamat, who graduated from Baylor College of Medicine in 2018. \u201cA couple of months later, I find out that the surgeon is Dr. Billy Cohn<\/a>, who is a huge name here. He\u2019s amazingly accessible. I reached out to him and he said: \u2018If you\u2019re really interested, show up.\u2019 He introduced me to TMCx (TMC Innovation\u2019s accelerator) and ever since then, I wanted to become more involved.\u201d<\/p>\n

\"\"

Ishan Kamat, M.D., MBA, TMC Biodesign 2020-2021 Fellow<\/p><\/div>\n

A heart surgeon and medical device inventor, Cohn is also executive director of the Johnson & Johnson Center for Device Innovation (CDI @ TMC)<\/a>\u2014a TMC Innovation partner housed down the hall at the TMC\u2019s John P. McGovern campus\u2014and vice president for Johnson & Johnson Medical Devices Companies.<\/p>\n

The cardiology team\u2019s Baylor College of Medicine mentors are Barbara Trautner, M.D., Ph.D.<\/a>, director of clinical and health services research in the department of surgery, and Scott LeMaire, M.D.<\/a>, vice chair for research in the department of surgery.<\/p>\n

The National Heart, Lung, and Blood Institute<\/a> of the National Institutes of Health<\/a> accepted the pair\u2019s proposal for a T32 training grant<\/a> to fund the preparation of post-doctoral fellows for careers in cardiovascular surgical research. Kamat, who won a fellowship in that program, also wanted to design cardiac devices.<\/p>\n

\u201cWe wrote the T32 grant with the idea that we would eventually be able to have a joint training program with the TMC Biodesign group and with the arrival of Ishan and his interests, we were able to bring our training programs together,\u201d Trautner said. \u201cHouston is such a good setting for more biotechnology startups given the strength of our medical center.\u201d<\/p>\n

LeMaire explained how Kamat will bridge the two programs.<\/p>\n

\u201cIt allows us to bring a fellow in and put them in an environment where they will learn not just the clinical side and the science side, which they can get from us, but they will learn about the business side and the commercialization side and all of the expertise required to actually get a product or idea into patients\u2014and that opportunity was just too good for us to pass up,\u201d he said.<\/p>\n

Baylor and TMC will share the equity stake in the cardiology project.<\/p>\n

Building on success<\/strong><\/p>\n

TMC Biodesign has spun out at least eight companies. Alleviant Medical<\/a>, launched from the 2016-2017 class, received TMC Venture Fund<\/a> investment to advance its interatrial shunt that provides pressure relief for patients with heart failure<\/a>. The last class produced TYBR Health<\/a> and its hydrogel spray<\/a> that reduces post-surgery scar formations, known as adhesions, and helps accelerate tissue regeneration.<\/p>\n

\u201cI think founding companies is really exciting. After doing it one time, my career aspiration was to be a serial founder. I didn\u2019t even know that was a career choice,\u201d Jaworski said. \u201cI think this was the absolute perfect opportunity to do that. You\u2019re literally getting paid to start a company. They give you so many resources and the network is absolutely incredible through this program.\u201d<\/p>\n

\"\"

Laura Ortiz-Velez, DVM, Ph.D., TMC Biodesign 2020-2021 Fellow<\/p><\/div>\n

It\u2019s the place where veterinarian Laura Ortiz-Velez, DVM, Ph.D.<\/a>, who earned her second doctorate in virology and microbiology from Baylor College of Medicine, feels she can advance her career. She already was working on her own company, based on technology developed at Baylor, to help inflammatory bowel disease (IBD) patients monitor intestinal information at home and believes that experience strengthened her fellowship application.<\/p>\n

\u201cThe biodesign program is attractive because it\u2019s about finding a great interdisciplinary team that complements your skills. You want to make a difference. You want to find a need you can help with and apply your knowledge to translate it into a product,\u201d she said.<\/p>\n

Ortiz-Velez was selected for the medical device team and offered a preview of where they\u2019re headed.<\/p>\n

\u201cNeurology and orthopedics are very attractive areas to us because we have backgrounds in those and they are both really hot right now,\u201d she said.<\/p>\n

TMC Biodesign bridges the gap between other TMC Innovation programs. TMC Alpha<\/a> works with everyone from grassroots tinkerers to scientists in the earliest stages of ideas or products to help them understand what it takes to become an entrepreneur. TMCx<\/a> is the accelerator for young companies. TMCx+<\/a> and TMCxi<\/a> provide office space for companies that want to grow in the innovation ecosystem.<\/p>\n

\u201cThese people are leaving their clinical practices and potential professional next steps to do this program. They understand that this is an amazing opportunity to focus their careers as entrepreneurs under the safety net of guaranteed salaries,\u201d Sakamoto said. \u201cThey know this is real. This is not an exercise. This is their life. This is their future.\u201d<\/p>\n

TMC BIODESIGN FELLOWS, 2020-2021<\/strong><\/p>\n

Digital Health Team<\/strong><\/p>\n

Nehal Swami<\/a><\/p>\n

Varun Kumar, M.D.<\/a><\/p>\n

Adam Hansen, Ph.D.<\/a><\/p>\n

Medical Device Team<\/strong><\/p>\n

Joe Upchurch, MBA<\/a><\/p>\n

Kirt Gill, M.D.<\/a><\/p>\n

Laura Ortiz-Velez, DVM, Ph.D.<\/a><\/p>\n

Cardiology Team (with Baylor College of Medicine)<\/strong><\/p>\n

Elizabeth \u201cEla\u201d Jaworski, Ph.D.<\/a><\/p>\n

Ishan Kamat, M.D., MBA<\/a><\/p>\n

Tyler Melton, MBA<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

The 2020-2021 cohort includes a third team focused on cardiology, marking a new collaboration with Baylor College of Medicine<\/p>\n","protected":false},"author":28,"featured_media":32794,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[1925,4880,451,4484,559,4876,56,4879,4877,4878,1458,4881,968,4779],"yoast_head":"\nTMC Biodesign expands startup fellowship beyond medical devices and digital health - TMC News<\/title>\n<meta name=\"description\" content=\"TMC Biodesign expands startup fellowship beyond medical devices and digital health with a cardiology team in the 2020-2021 cohort.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.tmc.edu\/news\/2020\/08\/tmc-biodesign-expands-startup-fellowship-beyond-medical-devices-and-digital-health\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TMC Biodesign expands startup fellowship beyond medical devices and digital health - 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