{"id":30863,"date":"2020-05-18T10:50:56","date_gmt":"2020-05-18T15:50:56","guid":{"rendered":"https:\/\/www.tmc.edu\/news\/?p=30863"},"modified":"2020-05-18T10:53:10","modified_gmt":"2020-05-18T15:53:10","slug":"phage-wars-fighting-antibiotic-resistance-with-microorganisms-found-in-sewers-and-bird-poop","status":"publish","type":"post","link":"https:\/\/www.tmc.edu\/news\/2020\/05\/phage-wars-fighting-antibiotic-resistance-with-microorganisms-found-in-sewers-and-bird-poop\/","title":{"rendered":"Phage wars: Fighting antibiotic resistance with microorganisms found in sewers and bird poop"},"content":{"rendered":"
Austen Terwilliger adjusted his hard hat and safety glasses. He had already fastened a long green rope to his plastic bucket, and he slowly began guiding it down into the sewage tank at a wastewater treatment plant in Houston. Terwilliger, who has a Ph.D. in molecular microbiology, was hunting for phages.<\/p>\n
Phages, the most abundant microorganism on the planet, can be found anywhere bacteria is present. Increasingly, phages are believed to be the most promising solution to the growing problem of antibiotic resistance, one of the biggest threats to global health today, according to the World Health Organization<\/a>.<\/p>\n :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: Short for bacteriophage, a phage is a virus that binds to bacteria. A phage injects its viral DNA into a bacterial cell and then replicates quickly until the cell ruptures, effectively destroying the cell and halting any bacterial infection. Unlike antibiotics\u2014which are composed of a fixed chemical structure that remains consistent\u2014phages have DNA that evolves alongside their bacterial counterparts. Bacteria is constantly evolving, so much so that some strains have adapted enough to resist modern medicine\u2019s most potent antibiotics. But because phages can evolve in tandem with their bacterial hosts, even a \u201csuper-bug\u201d bacterial strain resistant to antibiotics could be quelled with the counterpart phage\u2014hence Terwilliger\u2019s field trip to the sewer.<\/p>\n
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