{"id":13376,"date":"2019-03-04T17:28:47","date_gmt":"2019-03-04T17:28:47","guid":{"rendered":"https:\/\/www.tmc.edu\/news\/fda-cracks-down-on-companies-claiming-young-blood-as-the-fountain-of-youth\/"},"modified":"2019-08-16T15:04:51","modified_gmt":"2019-08-16T15:04:51","slug":"fda-cracks-down-on-companies-claiming-young-blood-as-the-fountain-of-youth","status":"publish","type":"post","link":"https:\/\/www.tmc.edu\/news\/2019\/03\/fda-cracks-down-on-companies-claiming-young-blood-as-the-fountain-of-youth\/","title":{"rendered":"FDA cracks down on companies claiming young blood as the fountain of youth"},"content":{"rendered":"

The U.S. Food and Drug Administration (FDA) has\u00a0issued an official warning<\/a> against the use of plasma infusions from “young blood” donors as anti-aging treatments.<\/p>\n

FDA Commissioner Scott Gottlieb, M.D., spoke out last month about establishments that claim to use the liquid form for blood from young donors to treat a variety of age-related conditions, including dementia, Alzheimer\u2019s disease, Parkinson\u2019s disease, multiple sclerosis, heart disease and post-traumatic stress disorder.<\/p>\n

\u201cThere is no proven clinical benefit of infusion of plasma from young donors to cure, mitigate, treat, or prevent these conditions, and there are risks associated with the use of any plasma product,\u201d Gottlieb said in a statement<\/a> on February 19, 2019. \u201cOur concerns regarding treatments using plasma from young donors are heightened by the fact that there is no compelling clinical evidence on its efficacy, nor is there information on appropriate dosing for treatment of the conditions for which these products are being advertised. Plasma is not FDA-recognized or approved to treat conditions such as normal aging or memory loss, or other diseases like Alzheimer\u2019s or Parkinson\u2019s disease.\u201d<\/p>\n

Plasma is the straw-colored liquid component of blood that contains a wealth of antibodies, glucose, clotting factors, electrolytes and hormones and, therefore, is considered \u201cthe gift of life.\u201d Plasma has many legitimate clinical uses in treating serious health problems\u2014including emergency situations (such as trauma and burns) and rare chronic conditions (such as autoimmune disorders and hemophilia).<\/p>\n

But over the years, companies have turned a profit selling this liquid gold\u2014offering plasma transfusions from young blood donors to people seeking to cheat aging, even though there\u2019s no scientific evidence to support those claims.<\/p>\n

One of these companies\u2014Ambrosia<\/a>, a private clinic based in Monterey, California, that was shut down after the FDA’s announcement\u2014charged patients a staggering $8,000 for a liter of young plasma and $12,000 for two liters for intravenous treatments purporting anti-aging benefits.<\/p>\n

There have been a series of scientific papers published in high-profile journals that used the same “young blood” theory to conduct experiments in mice. For example, in 2013, scientists from Stanford University published a study in Cell<\/em><\/a> in which they conjoined the veins of older mice to younger mice to circulate blood between the rodents. The results showed that a specific component in young blood had anti-aging benefits for older mice, sparking mainstream interest in potentially reversing aging in humans.<\/p>\n

\u201cWhat they found is, by using very specific measures, that they could see to some extent that if you had young blood in an older mouse, there were certain parameters and certain features of aging that were very slightly modified,\u201d said Margaret Goodell, Ph.D.<\/a>, professor and director of the Stem Cells and Regenerative Medicine Center (STaR) at Baylor College of Medicine. \u201cVice versa, you could take blood from an old mouse and put it into a younger mouse, and there were features of aging that you could now see in the young mouse. That led to the idea that there\u2019s something circulating in the blood that is associated with age that you can make you younger or older, depending on which direction it goes.\u201d<\/p>\n

However, these fountain-of-youth medical treatment claims \u201chave virtually no basis in reality,\u201d Goodell said.<\/p>\n

\u201cThere\u2019s a hunger in our culture for any anti-aging therapy,\u201d she said. \u201cEveryone wants to try something new, and this sounds kind of cool as if there\u2019s something magical in the blood of young people. It would be great if it were true, but it\u2019s just not. Frankly, what boggles my mind is the amount of money they\u2019re charging for these things.\u201d<\/p>\n

Even scientists who had done some of these early studies would argue, she said, that if there is any anti-aging effect at all, it\u2019s very small and very transient.<\/p>\n

\u201cYou could imagine if there\u2019s a grain of reality to what is going on, that\u2014at best\u2014somebody might have a very transient, extremely minor effect that you\u2019re not really going to be able to detect,\u201d Goodell said. \u201cThat\u2019s going to be gone in, say, a week after the transfusion is done. How often would you have to do these transfusions and at what cost for it to have an effect? It\u2019s just not possible.\u201d<\/p>\n

Over at least the last eight decades, there has been a surge in research aimed at understanding the fundamental mechanisms of aging and the possibility of slowing down the process. The National Institutes of Health spent an estimated $8.1 billion<\/a> on aging, dementia and Alzheimer\u2019s disease research in 2018, according to the NIH\u2019s Research Portfolio Online Reporting Tools.<\/p>\n

The 2019 budget for these conditions and diseases is expected to be less, which creates a more difficult funding challenge for researchers.<\/p>\n

\u201cIn real science, we\u2019re always struggling for funding to do what we think is good, quality research experiments,\u201d Goodell said. \u201cI work on aging myself and its impact on stem cells, as do many other labs. We\u2019re always scrounging around for dollars here and there. Then I see people spending $8,000 on infusing plasma and the other people doing that. If we had 10 of them, that\u2019s $80,000 I could put to really great use in a lab. I feel like it\u2019s a terrible waste of money that\u2019s going into the pockets of charlatans.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

The U.S. Food and Drug Administration (FDA) has\u00a0issued an official warning against the use of plasma infusions from “young blood” donors as anti-aging treatments. FDA Commissioner Scott Gottlieb, M.D., spoke out last month about establishments that claim to use the liquid form for blood from young donors to treat a variety of age-related conditions, including […]<\/p>\n","protected":false},"author":15,"featured_media":13377,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[47,3523,3522],"yoast_head":"\nFDA cracks down on companies claiming young blood as the fountain of youth - TMC News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.tmc.edu\/news\/2019\/03\/fda-cracks-down-on-companies-claiming-young-blood-as-the-fountain-of-youth\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FDA cracks down on companies claiming young blood as the fountain of youth - TMC News\" \/>\n<meta property=\"og:description\" content=\"The U.S. Food and Drug Administration (FDA) has\u00a0issued an official warning against the use of plasma infusions from “young blood” donors as anti-aging treatments. 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