{"id":13266,"date":"2019-02-05T19:24:37","date_gmt":"2019-02-05T19:24:37","guid":{"rendered":"https:\/\/www.tmc.edu\/news\/mending-a-hole-in-the-heart\/"},"modified":"2020-02-05T12:56:19","modified_gmt":"2020-02-05T18:56:19","slug":"mending-a-hole-in-the-heart","status":"publish","type":"post","link":"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/","title":{"rendered":"Mending a hole in the heart"},"content":{"rendered":"<p>Before birth, babies rely on their mothers for oxygen. A mother\u2019s oxygen-rich blood travels from the right atrium to the left atrium of a baby\u2019s developing heart through a small, open flap called the foramen ovale.<\/p>\n<p>All babies are born with this tiny hole in their hearts, but in most cases the hole closes within six months. For a quarter of the population, though, the hole never closes, a condition known as patent foramen ovale (PFO). This opens the door for recurring strokes.<\/p>\n<p>Enter <a href=\"https:\/\/www.memorialhermann.org\/doctors\/cardiovascular-disease-specialists\/dr-richard-smalling-md-1207\/\">Richard Smalling, M.D., Ph.D.<\/a>, director of interventional cardiology with <a href=\"https:\/\/med.uth.edu\">McGovern Medical School<\/a> at UTHealth and the <a href=\"https:\/\/heart.memorialhermann.org\">Memorial Hermann Heart &amp; Vascular Institute<\/a>-Texas Medical Center. Smalling led an eight-year nationwide clinical trial to study the safety and efficacy of the Amplatzer PFO Occluder, a device that can patch up this congenital heart defect in less than an hour. The trial ended in late 2011 and follow-up data from nearly six years later shows the device reduces the risk of recurrent stroke by 45 to 62 percent.<\/p>\n<p>\u201cThe beauty of it is: It\u2019s delivered via a catheter that we insert through a vein in the leg,\u201d Smalling explained.<\/p>\n<p>The PFO Occluder is outfitted with two discs made of woven nickel titanium mesh, one the size of a nickel and the other the size of a quarter.<\/p>\n<p>Before the device is inserted in the catheter, it is stretched to assume the shape of the tube. Once the catheter enters the left atrium through the hole in the heart, the smaller mesh disc expands and tugs against the wall between the heart\u2019s two upper chambers to collapse the flap. The second, larger disc springs open as the catheter is retracted in the right atrium. With the flap securely sandwiched between both discs, heart tissue heals over the device within six months, creating a new wall between the two upper chambers of the heart.<\/p>\n<p>According to Smalling, the device, which has been approved by the U.S. Food and Drug Administration, provides a simple, yet elegant, solution for many patients. \u201cWith the device, we can at least eliminate one cause of recurrent stroke,\u201d he said.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Before birth, babies rely on their mothers for oxygen. A mother\u2019s oxygen-rich blood travels from the right atrium to the left atrium of a baby\u2019s developing heart through a small, open flap called the foramen ovale. All babies are born with this tiny hole in their hearts, but in most cases the hole closes within [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":13267,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[3459,3458,3457],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mending a hole in the heart - TMC News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mending a hole in the heart - TMC News\" \/>\n<meta property=\"og:description\" content=\"Before birth, babies rely on their mothers for oxygen. A mother\u2019s oxygen-rich blood travels from the right atrium to the left atrium of a baby\u2019s developing heart through a small, open flap called the foramen ovale. All babies are born with this tiny hole in their hearts, but in most cases the hole closes within [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/\" \/>\n<meta property=\"og:site_name\" content=\"TMC News\" \/>\n<meta property=\"article:published_time\" content=\"2019-02-05T19:24:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-02-05T18:56:19+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2019\/06\/pfo-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2000\" \/>\n\t<meta property=\"og:image:height\" content=\"1400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Shanley Pierce\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Shanley Pierce\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/\"},\"author\":{\"name\":\"Shanley Pierce\",\"@id\":\"https:\/\/www.tmc.edu\/news\/#\/schema\/person\/b39cb2d1ede8d278ee8693200f44ced4\"},\"headline\":\"Mending a hole in the heart\",\"datePublished\":\"2019-02-05T19:24:37+00:00\",\"dateModified\":\"2020-02-05T18:56:19+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/\"},\"wordCount\":363,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.tmc.edu\/news\/wp-content\/uploads\/sites\/2\/2019\/06\/pfo-1.jpg\",\"keywords\":[\"patent foramen ovale\",\"PFO Occluder\",\"Smalling\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/\",\"url\":\"https:\/\/www.tmc.edu\/news\/2019\/02\/mending-a-hole-in-the-heart\/\",\"name\":\"Mending a hole in the heart - 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