Zhen Gu, Ph.D.: Leverage Physiology for Bioresponsive Drug Delivery

Wednesday, March 27, 2019 | 3:00 p.m. – 4:00 p.m. Add to Calendar

Zhen Gu, PhD
Department of Bioengineering
California NanoSystems Institute (CNSI)
University of California, Los Angeles

Spurred by recent advances in materials chemistry, molecular pharmaceutics and nanobiotechnology, stimuli-responsive “smart” systems offer opportunities for precisely delivering drugs in dose-, spatial- and temporal-controlled manners. Dr. Gu will present ongoing efforts to develop physiological signal-triggered bioinspired drug delivery systems. First, he will present the glucose-responsive synthetic systems for biomimetic delivery of insulin for diabetes treatment, emphasizing bioresponsive microneedle patches and vesicle fusion-mediated synthetic beta cells. He also will include the local and targeted delivery of immunomodulatory therapeutics for enhanced cancer therapy. Specifically, he will introduce his latest study utilizing platelets, cell conjugates and sprayable gels for delivery of immune checkpoint inhibitors.


Houston Methodist Hospital

6565 Fannin St., Houston, TX 77030


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