Press Releases

Adults Who Mix Cannabis with Opioids for Pain Report Higher Anxiety, Depression


opiods-and-marijuana-1-newsroom A new study of adults who combine prescription opioids and cannabis revealed elevated anxiety and depression symptoms, with no increased pain reduction.
By Laurie Fickman, University of Houston | August 12, 2019

A researcher from the University of Houston has found that adults who take prescription opioids for severe pain are more likely to have increased anxiety, depression and substance abuse issues if they also use marijuana.

“Given the fact that cannabis potentially has analgesic properties, some people are turning to it to potentially manage their pain,” Andrew Rogers, said in describing the work published in the Journal of Addiction Medicine. Rogers focuses on the intersection of chronic pain and opioid use, and identifying the underlying psychological mechanisms, such as anxiety sensitivity, emotion regulation, pain-related anxiety, of these relationships. Rogers is a doctoral student in clinical psychology who works in the UH Anxiety and Health Research Laboratory and its Substance Use Treatment Clinic.

Under the guidance of advisor Michael Zvolensky, Hugh Roy and Lillie Cranz Cullen Distinguished University Professor of psychology and director of the lab and clinic, Rogers surveyed 450 adults throughout the United States who had experienced moderate to severe pain for more than three months. The study revealed not only elevated anxiety and depression symptoms, but also tobacco, alcohol, cocaine and sedative use among those who added the cannabis, compared with those who used opioids alone. No increased pain reduction was reported.

Importantly, said Rogers, while the co-use of substances generally is associated with poorer outcomes than single substance use, little work has examined the impact of mixing opioids and cannabis.

Opioid misuse constitutes a significant public health problem and is associated with a host of negative outcomes. Despite efforts to curb this increasing epidemic, opioids remain the most widely prescribed class of medications. Prescription opioids are often used to treat chronic pain, despite the risks, and chronic pain remains an important factor in understanding this epidemic.

Cannabis is another substance that has recently garnered attention in the chronic pain literature, as increasing numbers of people use it to manage chronic pain.

“There’s been a lot of buzz that maybe cannabis is the new or safer alternative to opioid, so that’s something we wanted to investigate,” said Rogers, who said the idea for the study evolved from a conversation with Zvolensky. Rogers was studying opioid use and pain management when they began discussing the role of cannabis in managing pain.

“The findings highlight a vulnerable population of polysubstance users with chronic pain and indicates the need for more comprehensive assessment and treatment of chronic pain,” said Rogers.




Social Posts

profile_image

MD Anderson Cancer Center

@MDAndersonNews

Myth: #Pain is just physical.Learn the truth from our @uzo_md and read his advice for getting the right treatment: https://t.co/wIXQFSImcE #endcancer

6 hours ago
profile_image

Veterans Affairs

@DeptVetAffairs

Tens of thousands of volunteers laid wreaths at VA national cemeteries across the U.S. as part of National Wreaths Across America Day Dec. 14. https://t.co/ENkDR3bqxB

8 hours ago
profile_image

MD Anderson Cancer Center

@MDAndersonNews

“We need to better understand why #probiotics don’t help and may even be harmful,” says our @carrie_d_mac of the microbiome’s link to the effectiveness of #immunotherapy. #endcancer https://t.co/t6fulbhDcH

9 hours ago
profile_image

BCMHouston

@bcmhouston

Learn how Dr. Zachary Pallister stays fit in this week's Healthy Habits. https://t.co/GLO29z2W2u #healthy #habits

10 hours ago
profile_image

Veterans Affairs

@DeptVetAffairs

VA mom helping women Veterans… inspired by her Navy daughter https://t.co/immmo4yLt9 via #VAntagePoint

10 hours ago
profile_image

MD Anderson Cancer Center

@MDAndersonNews

“When I first made eye contact with @MAOnstad, I knew I was where I was supposed to be,” says #uterinecancer survivor Tralisa Woods: https://t.co/iCEfVL0tGj #gyncsm #endcancer

11 hours ago
profile_image

Veterans Affairs

@DeptVetAffairs

VA’s Office of Mental Health and Suicide Prevention supports proposed three-digit dialing code for suicide hotline https://t.co/a6hiRA6I7Q via #VAntagePoint

12 hours ago
profile_image

Memorial Hermann

@memorialhermann

@skologinczak We'd like to hear more about your experience. Please send your contact information and Memorial Hermann location to help@memorialhermann.org so we can look into this.

14 hours ago
profile_image

Memorial Hermann

@memorialhermann

@skologinczak We'd like to hear more about your experience. Please send your contact information and Memorial Hermann location to help@memorialhermann.org so we can look into this.

14 hours ago
profile_image

BCMHouston

@bcmhouston

Wondering what you should be eat to fuel your workout? Registered dietitian, Roberta Anding, breaks it down. https://t.co/BRhtzvO48R #exercise #workouts

14 hours ago
profile_image

Houston Methodist

@MethodistHosp

@Nanomed_hmri Appreciate the share.

15 hours ago
profile_image

Houston Methodist

@MethodistHosp

@RobertaS_CIO @InnoMapHou @nataliejharms Appreciate the shout-out.

15 hours ago
profile_image

Houston Methodist

@MethodistHosp

@lifecourseUofT Thanks for the shout-out.

15 hours ago
profile_image

BCMHouston

@bcmhouston

Dr. Atif Iqbal with @BCM_Surgery discusses the human papillomavirus virus and the rise of anal cancer. https://t.co/GhsLd2flaJ #HPV

16 hours ago
profile_image

University of Houston

@UHouston

RT @UHCougars: .@UHouston students, don't forget to claim your ticket!Don't miss out on a 👔𝘽𝙇𝙐𝙀 𝙎𝙃𝙄𝙍𝙏 𝙍𝙀𝘿 𝙏𝙄𝙀 𝙏-𝙎𝙃𝙄𝙍𝙏!! 🤯🎟️| https://…

1 day ago