Innovation

Grant boosts consortium’s pediatric device development


By Christine Hall | August 27, 2018

Pediatric medical device innovators across the Texas Medical Center—and beyond—will receive the critical support and resources needed to develop novel health care solutions for sick children thanks to a new $6.75 million, five-year grant.

The Southwest National Pediatric Device Consortium (SWPDC), anchored by Texas Children’s Hospital and Baylor College of Medicine, received a prestigious P50 grant from the U.S. Food & Drug Administration that begins on Sept. 1, 2018.

Chester Koh, M.D.

Often, surgeons shrink adult devices to fit children. Instead, Chester Koh, M.D., SWPDC founder and lead principal investigator, hopes device makers will do the opposite—start with pediatric-sized devices and scale up to adult. For example, some of the smallest heart valves available might be 8 millimeters in diameter, but need to be as small as 3 millimeters for an infant or child.

“It is well known, and acknowledged by the FDA, that pediatric devices are five to 10 years behind adult devices,” said Koh, who is also works as a pediatric urologist at Texas Children’s and professor of urology, pediatrics and obstetrics/gynecology at Baylor. “However, pediatric patients still need devices, so we need to serve our patients.”

The consortium includes clinical, scientific/engineering, investment, regulatory and academic partners in the Texas Medical Center, the greater Houston area and the southwestern U.S. The collaborative aims to address the shortage of needed devices for pediatric health conditions by supporting innovators.

The grant will enable the consortium to fund projects directly and bring in consultants to help with the devices, something innovators were not able to do before, Koh said.

RELATED STORY: Pediatric Medical Device Development

The collaborative will also attract what Koh calls “untapped resources” such as pediatric clinicians who see a need for a device but who may have not had development training. The consortium can provide the resources to help them develop a solution, build a prototype and proceed to the next steps of getting the device into clinics and operating rooms.

The primary consortium partners include Texas A&M University, Rice University, University of Houston and Fannin Innovation Studio, and includes others such as Biotex Inc., Children’s Hospital of San Antonio, Children’s Health in Dallas and Phoenix Children’s Hospital. SWPDC was selected as one of five national consortia that are addressing the shortage of pediatric devices.

The five principal investigators include Koh and Henri Justino, M.D., of Texas Children’s and Baylor; biomedical engineer Balakrishna Haridas, Ph.D., of Texas A&M University; bioengineer Maria Oden, Ph.D., of Rice University; and Michael Heffernan, Ph.D., also a bioengineer, of Fannin Innovation Studio in Houston.

Justino, director of the Charles E. Mullins Cardiac Catheterization Laboratories at Texas Children’s, was recently part of the TMC Innovation Institute’s TMCx medical device accelerator program with his company, Polyvascular, which creates tiny replacement heart valves for treating pediatric congenital heart disease.

RELATED STORY: Tiny Valves for Tiny Bodies

Koh said TMC Innovation, and its programs including TMCx, Johnson & Johnson Innovation’s JLABS @ TMC, and J&J’s Center for Device Innovation, will play a role in this initiative as well.

“This is really a collaborative effort across the Texas Medical Center to help accelerate the products,” Koh said. “We are basically going to serve as navigators to help pediatric innovators get the right expertise so they are able to go all the way from an idea to commercialization—what we call the total product life cycle.”




Social Posts

profile_image

Harris Health System

@harrishealth

Going through menopause can be a bit like traveling in a new city without a map—or even a clear destination. In fact, you may not even realize you’re there until you’ve passed it. Here's how to better cope with this midlife milestone. https://t.co/6s25Aji4oe https://t.co/YUNpLFz3hh

35 mins ago
profile_image

Veterans Affairs

@DeptVetAffairs

.@VANatCemeteries Veteran sees duty at 35 locations https://t.co/aFx133klvV #VAntagePoint

36 mins ago
profile_image

Memorial Hermann

@memorialhermann

Let’s bring to light some surprising habits that could be damaging your skin: https://t.co/7VXEaHA9CT. https://t.co/dioqIgDfHD

36 mins ago
profile_image

UTHealth

@UTHealth

Vitiligo, Alopecia Merely Cosmetic? Think Again https://t.co/IrsX5jsoMq

51 mins ago
profile_image

MD Anderson Cancer Center

@MDAndersonNews

You don’t need any equipment to do #strengthtraining. Here are our tips for an at-home workout: https://t.co/B6LU00kIH9 @FocusedonHealth #endcancer https://t.co/fjCJ2TuPz5

1 hour ago
profile_image

BCMHouston

@bcmhouston

Running and enjoying treats in moderation are just some of the ways Dr. Christina Weng stays fit. See more of her healthy habits: https://t.co/ttuEhmpRmU #healthy #habits https://t.co/NNehV0jfJD

1 hour ago
profile_image

Texas Children's

@TexasChildrens

Join us for season two of @TexasChildrens podcast series, Outcomes! Every day incredible stories occur inside our walls, here are a few of those such stories.--> https://t.co/73SXLUB5Pv (Don't forget to subscribe!) https://t.co/fA7C3hgMgJ

1 hour ago
profile_image

Veterans Affairs

@DeptVetAffairs

RT @SecWilkie: I had the opportunity to share my command philosophy “Walk the Post" at VHA’s NLC meeting earlier today. I am honored to b…

1 hour ago
profile_image

UTHealth

@UTHealth

This could be why your hands are always so cold: https://t.co/T6p3d32EZS

2 hours ago
profile_image

UTHealth

@UTHealth

As Jay McIntosh aged, he noticed tremors he had for years began to progress throughout his body as well, affecting his hands, feet, and head. Find out how the care Jay received from @UTPhysicians restored his quality of life: https://t.co/5WlQAtYGl2

2 hours ago
profile_image

TexasHeartInstitute

@Texas_Heart

RT @isiahcareyFOX26: Amazing story by the staff at TMC News and edited by our good friend @CindyGeorge https://t.co/KHcTqCVp1h!

2 hours ago
profile_image

TexasHeartInstitute

@Texas_Heart

RT @KeriKimler: @isiahcareyFOX26 @cindygeorge Thank you Isiah, @FOX26Houston and our friends Cindy and @ShanleyChien at the TMC. @Texas_Hea…

2 hours ago
profile_image

TexasHeartInstitute

@Texas_Heart

Celebrating #WorldBookDay with some Cooley classics and translations. https://t.co/6ri3LQXBj1

2 hours ago
profile_image

Harris Health System

@harrishealth

Harris Health's Stroke of Hope Support Group is free and open to all stroke survivors, caregivers and families of stroke patients. Support group meets first Wednesday of each month. https://t.co/sDOqlBkBWR https://t.co/YUorfPKRBp

2 hours ago
profile_image

TAMU Health Sciences

@TAMHSC

It's time for the big game! Come and join us at Veteran's Park on Friday, April 26, from 6 - 8:30pm for the @TAMHSC Powder Puff game between @TAMUmedicine and @TAMUnursing. #TAMUHealth #GameDay #AggieDocs #AggieNurses https://t.co/ukqszafIaX

2 hours ago