Baylor College of Medicine is among a national network of health care institutions and collaboratives recruiting for what is described as the largest coordinated research study of aggressive prostate cancer in African American men.
An estimated 30,000 African American men were diagnosed with prostate cancer in 2016, according to the American Cancer Society’s most recent figures, and the disease is believed to have killed more than 4,400 black men that year. Black men are twice as likely to die from prostate cancer than white men and have the highest death rate from the disease among all racial or ethnic groups in the United States, findings show.
Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Tumor Markers, and Social Stress—also known as RESPOND—is a $26.5-million, multi-institutional study funded by the National Cancer Institute, the National Institute on Minority Health and Health Disparities and the Prostate Cancer Foundation.
RESPOND will examine the impact of social stressors such as discrimination along with socioeconomic status, education, home life, residence location and early life events as well as genetic and biological factors in the development and progression of prostate cancer in African American men. The study also will explore why black men are at higher risk for developing more aggressive forms of the disease and why their mortality rate is higher.
Leading the study for Baylor is Melissa Bondy, Ph.D., professor of medicine – epidemiology and population sciences and associate director of cancer prevention and population sciences in the Dan L Duncan Comprehensive Cancer Center.
“While looking at cases, Texas stood out,” she said. “Some 1,700 African American men are diagnosed in Texas annually.”
The study aims to recruit 10,000 African American men nationwide over the next five years. Each participant will be asked to provide a saliva sample and allow researchers to access his prostate cancer biopsy tissue. The samples will be analyzed to identify genetic markers of prostate cancer and unique tumor characteristics.
Recruiting this population may be a challenge, said Bondy, who has previously sought participants for breast cancer research. This will be her first time recruiting for prostate cancer.
She noted that men, in general, don’t like to participate in research, but said the prostate cancer researchers are getting creative in their approach by looking at recruitment through barbershops.
“We may have to rethink how to do this,” she said. “This is a hard group to reach. They are not used to participating in research and tend to be older men. They are also more curious about what we will do with the information.”
Bondy hopes to enroll about 3,000 study participants from Texas with a process that will kick off with focus groups this summer. Recruitment begins in January.
The Keck School of Medicine at the University of Southern California will lead the study. Other participating institutions include Rutgers Cancer Institute of New Jersey with the New Jersey Department of Health, Public Health Institute with the Cancer Registry of Greater California, Emory University, Dana-Farber Cancer Institute with Harvard University, Johns Hopkins University, Louisiana State University Health New Orleans, Moffitt Cancer Center, Barbara Ann Karmanos Cancer Institute with Wayne State University and the University of California, San Francisco.
ASHEVILLE, NC: Robotic pets give Asheville Veterans a source of companionship at the VA https://t.co/UHsWNlhWcn via @WLOS_13
12 Most Filling Fruits and Vegetables, According to Nutritionists https://t.co/jB0yXu87qc
How our team is using exercise to help target #cancer tumors with #chemotherapy: https://t.co/sDAb3iSCXt @SchadlerLab @mkatzmd @DrNgoHuang @DrValeraeLewis #endcancer
Students, teachers, volunteers give Veterans a proper welcome home https://t.co/OFTUWzEAxT via @fox43
Professor passionate about helping women wins prestigious teaching honor - UTHealth News: https://t.co/mRwCvmHHfI
They are only about half an inch, but see how the hookworm impacted the South. https://t.co/GiHRNWPbDe #hookworms #infectiousdiseases
RT @GoutAlliance: @GoutEducation A1: Gout is a form of inflammatory arthritis – a fact that many people still don’t know. You can learn mor…
When her brother was diagnosed with renal medullary carcinoma, a rare form of #kidneycancer, Cora Connor got to work advocating for more research: https://t.co/ygAHxi2akl #kcsm #endcancer https://t.co/aDAOqBh24c
Today we honor Army Veteran Melvin Anderson in remembrance of his service and sacrifice for our country https://t.co/WLWaoRQSqy #VeteranOfTheDay #CarryTheLoad #NoVeteranEverDies
@MaryBethMosley Thanks for sharing.
@Houston_BCH Thanks for the shout-out
RT @BCMEthics: You may soon need to be 21 to buy #tobacco products in Texas. Our @SMorain discusses what this bill might accomplish, and wh…
RT @UTMBProvost: The third quarter of FY19 has been exceptional for UTMB researchers publishing their work. UTMB researchers had 344 public…
RT @BCM_Surgery: Another great mentor from @bcmhouston and @TexasChildrens Dr. Edward Buchanan was selected as the 2019 Research Mentor in…
Research #nurse Meghan Meyer says the relationships she builds with patients enrolled in clinical trials are “the best part of my job.” https://t.co/t6QmqZBcKl #endcancer