William McKeon, president and CEO of the Texas Medical Center, kicks off TMCx Demo Day.
Raiing Medical
Alleviant Medical
Erik Halvorsen, Ph.D., director of the TMC Innovation Institute.
iSono Health
The companies gather on stage for the last time.

TMCx Graduates 18 Medical Device Companies

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TMCx Graduates 18 Medical Device Companies

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It was standing room only on Nov. 8, as the Texas Medical Center Innovation Institute held its fall TMCx Demo Day.

Eighteen medical device companies pitched for the final time on the main stage in front of an audience of more than 300 hospital stakeholders, key opinion leaders and investors as part of the TMCx accelerator program.

This was the fifth program for TMCx, which provides a comprehensive and practical curriculum to assist participating founders on their entrepreneurial path. Successful investors, entrepreneurs, subject-matter experts, industry professionals and hospital leaders guide each startup in the areas of intellectual property, product development, regulatory strategies, health policy, marketing, fundraising, contract negotiations and communications.

Companies accepted into the new cohort include:

  • Aesela (Houston) – Wearable photobiomodulation device designed to accelerate and enhance post-surgical recovery.
  • Alleviant Medical (Houston) – Transcatheter technology to provide left atrial decompression and symptomatic relief for congestive heart failure.
  • Bitome (Boston) – MRI-based diagnostic tool for non-invasive monitoring of the human hydration state.
  • Dock Technologies (Madison, Wis.) – Electronic wristbands that provide a visual reminder of time elapsed, helping care teams quickly navigate complex treatment processes.
  • Elsius Biomedical (Calgary, Canada) – Portable Extracorporeal Membrane Oxygenation unit that includes a proprietary coating to enhance biocompatibility and prevent blood clots.
  • Forest Devices (Pittsburgh) – Screening device that enables identification of stroke patients and triage to the right level of care.
  • iSono Health (San Francisco) – Accessible breast-health monitoring combining 3D ultrasound and artificial intelligence.
  • Multisensor Diagnostics (Baltimore, Md.) – Device that measures multiple vital signs by mouth in less than a minute.
  • NanoEar Technologies (Houston) – A minimally-invasive, micro-implantable hearing aid, positioned to disrupt the market by utilizing Direct Eardrum Modulation.
  • NAVi Medical Technologies (Melbourne, Australia) – Improving neonatal umbilical venous catheter placements by providing clinicians with real-time feedback on the location of the catheter tip.
  • Orphidia (San Francisco) – Portable blood diagnostic platform providing lab-quality test results in 20 minutes.
  • PolyVascular (Houston) – Polymeric transcatheter valves for children with congenital heart disease.
  • Raiing Medical (Boston) – Wearable device monitoring vital signs for connected health.
  • Replete Biotics (Houston) – Standardizes fecal specimen processing while protecting bacterial community integrity and eliminating cross-contamination risks.
  • Resthetics (Houston) – Device to convert waste anesthesia into a safe renewable resource.
  • Sonavex (Baltimore, Md.) – Implantable device that utilizes ultrasound to detect blood clots after surgery.
  • Vena Medical (Ontario, Canada) – Making vascular procedures faster, easier and safer by providing physicians with a thin fiberoptic camera that sees through blood.
  • Vitls (San Francisco) – Vital signs platform for continuous, remote monitoring.

Also announced at Demo Day was the new $25 million TMC Venture Fund, an initiative designed to support technologies and early-stage companies in Houston’s health care ecosystem and further the TMC’s mission to advance health, education and research. Five former TMCx companies were awarded initial funds, including Alleviant Medical, Briteseed, CNSDose, Medable and Noninvasix.


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