Spotlight on JLABS
Interested in starting a company, investing, or just curious about the current state of innovation in Houston? Then YOU are invited to JLABS @ TMC on September 20th to meet, greet, and see short presentations on some of our standout companies. Space is limited, so don’t miss out!
Did you know that JLABS @ TMC is home to nearly 35 emerging companies? On September 20th, JLABS will shine the spotlight on three of our resident companies: Courier Therapeutics, Intuitap, and Wntrix. Join us to see how they’re moving innovation forward, right here in Houston. Please note that the presentations at this event will include publicly available, non-confidential information only.
Wednesday, September 20, 2017
11:15 a.m. | Registration Opens
11:30 a.m. | Networking Lunch
12:00 p.m. | Presentations
1:00 p.m. | Program Close
Courier Therapeutics read more»
Intuitap read more»
Wntrix read more»
Please RSVP online so that we can get an accurate headcount for food and beverages.
JLABS @ TMC
John P. McGovern Campus
2450 Holcombe Blvd, Suite J
Houston, TX 77021
Presenting Companies’ Descriptions:
Courier is developing a platform technology for precise delivery of cytokines to NK and T cells. The core technology is based on observations about viral stealth proteins that have evolved over millions of years to target certain receptors with extremely high affinity. This enables us to eliminate off target effects of cytokine therapy while increasing efficacy. High dose IL2 therapy is relatively effective but has significant drawbacks in toxicity.
Courier has designed a fusion protein that eliminates the off-target effects. Responders to IL2 have highly durable responses, but serious toxicity is seen in the areas of hepatoxicity and vascular leak syndrome. There is a 2% patient death rate, and 50% of patients discontinue therapy due to the toxicity.
IntuiTap eliminates the guesswork, frustration, and pain from spinal punctures by providing physicians real-time visualization of the underlying vertebrae. The handheld and easy-to-use IntuiTap is the world’s first tactile imaging device designed specifically to help position and guide a spinal needle for lumbar punctures, anesthesia, and epidurals.
IntuiTap also eliminates the need for unreliable and cumbersome manometers for pressure measurement by incorporating a continuous, digital pressure sensor and readout. This minimizes the incidence of failure and allows physicians to quickly and accurately get the pressure data they need. Additionally, IntuiTap makes it easy to sequentially collect cerebrospinal fluid while minimizing the chance of exposure to potentially contaminated fluid.
Overall, IntuiTap’s cutting-edge technology improves efficiency, decreases procedural costs, and instills confidence in both clinicians and patients, alike.
The company is focused on developing antibody-based therapeutics against targets in the Wnt signaling pathway for the treatment of cancers that are driven by the intended targets. In particular, the company will license preclinical candidates from the co-founder of the company that target receptors mutated in significant populations of lung, liver, and colon cancer. The company will optimize the candidates and develop them into IND candidates.Wnt Signaling is mutated in almost 100% of colon cancer and 20-50% of liver cancer, and in a significant proportion of other types of solid tumors. Several drugs targeting the Wnt system are under development. However, currently there are no drugs targeting the Wnt system on the market as direct targeting of the system has been challenging due to various reasons.
The co-founder Qingyun (Jim) Liu was the first to discover a novel ligand receptor system that regulate the Wnt signaling system with a driving role in lung adenocarcinoma. This will allow Wntrix to overcome the challenges others have experiencedWnt Signaling is mutated in almost 100% of colon cancer and 20-50% of liver cancer, and in a significant proportion of other types of solid tumors.
Johnson and Johnson Innovation, JLABS
2450 Holcombe Blvd. Suite J