Michael Diehl, PhD: Resolving Integrated Scaffold Protein Functions in Living Cells
The Department of Nanomedicine presents:
Michael Diehl, PhD
Associate Professor of Bioengineering
Associate Professor of Chemistry
The nodes of many signaling pathways and regulatory networks are controlled by scaffolding proteins which assemble multiple proteins into large complexes and signaling stations. Assembly of these complexes allows cells to integrate signals and orchestrate the dynamics of downstream pathway components. Signaling scaffolds are widely recognized as crucial to cell physiology.
Various scaffold proteins have been identified as markers in cancer and other diseases. Nevertheless, the dynamic functions of these complexes remain very difficult to study. In this lecture, Michael Diehl, PhD, will describe how new microscopy approaches can be used for leveraging imaging analyses of endosome development to dissect the dynamic functions of scaffolds and resolve the architecture of their integrated regulatory network.
For lecture abstract and location information, visit: events.houstonmethodist.org/michael-diehl
Houston Methodist Research Institute
6670 Bertner Ave.
Houston, Texas 77030
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