Chalermchai Khemtong, PhD: Probing the Metabolism of Disease by Hyperpolarized 13C MRI
Houston Methodist Research Institute presents:
Chalermchai Khemtong, PhD
Advanced Imaging Research Center & Department of Radiology
University of Texas Southwestern Medical Center
The analysis of biological processes such as energy metabolism is an important feature in the diagnosis and therapy of diseases. Despite current advancements in clinical imaging technologies, in vivo characterization of real-time metabolism remains challenging. It has now been demonstrated that hyperpolarized 13C magnetic resonance imaging (MRI) can be used to visualize real-time metabolism in diseased tissues such as tumors and abnormal myocardium.
Chalermchai Khemtong, PhD, and his laboratory at UT Southwestern is employing this non-invasive technology, paired with traditional magnetic resonance spectroscopy, to study substrate metabolism in the heart, liver, and tumors, to identify imaging biomarkers as well as to establish imaging methods for the in vivo characterization of diseases. In this talk, Khemtong will present his recent works on oxidation of hyperpolarized 13C-enriched substrates in healthy and diseased hearts. Hyperpolarized 13C-enriched agents for imaging tumor microenvironments will also be discussed.
For lecture abstract and location information, visit: events.houstonmethodist.org/chalermchai-khemtong
Houston Methodist Research Institute
6670 Bertner Ave.
Houston, Texas 77030
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