at Texas Children’s Hospital, Daniel Harrington, Ph.D., assistant professor at The University
of Texas Health Science Center at Houston, and Kwon Soo Chun, Ph.D., a pediatric cardiology
instructor at Baylor College of Medicine, display PolyVascular pediatric heart valves.
Pediatric medical device innovators across the Texas Medical Center—and beyond—will receive the critical support and resources needed to develop novel health care solutions for sick children thanks to a new $6.75 million, five-year grant.
The Southwest National Pediatric Device Consortium (SWPDC), anchored by Texas Children’s Hospital and Baylor College of Medicine, received a prestigious P50 grant from the U.S. Food & Drug Administration that begins on Sept. 1, 2018.
Often, surgeons shrink adult devices to fit children. Instead, Chester Koh, M.D., SWPDC founder and lead principal investigator, hopes device makers will do the opposite—start with pediatric-sized devices and scale up to adult. For example, some of the smallest heart valves available might be 8 millimeters in diameter, but need to be as small as 3 millimeters for an infant or child.
“It is well known, and acknowledged by the FDA, that pediatric devices are five to 10 years behind adult devices,” said Koh, who is also works as a pediatric urologist at Texas Children’s and professor of urology, pediatrics and obstetrics/gynecology at Baylor. “However, pediatric patients still need devices, so we need to serve our patients.”
The consortium includes clinical, scientific/engineering, investment, regulatory and academic partners in the Texas Medical Center, the greater Houston area and the southwestern U.S. The collaborative aims to address the shortage of needed devices for pediatric health conditions by supporting innovators.
The grant will enable the consortium to fund projects directly and bring in consultants to help with the devices, something innovators were not able to do before, Koh said.
RELATED STORY: Pediatric Medical Device Development
The collaborative will also attract what Koh calls “untapped resources” such as pediatric clinicians who see a need for a device but who may have not had development training. The consortium can provide the resources to help them develop a solution, build a prototype and proceed to the next steps of getting the device into clinics and operating rooms.
The primary consortium partners include Texas A&M University, Rice University, University of Houston and Fannin Innovation Studio, and includes others such as Biotex Inc., Children’s Hospital of San Antonio, Children’s Health in Dallas and Phoenix Children’s Hospital. SWPDC was selected as one of five national consortia that are addressing the shortage of pediatric devices.
The five principal investigators include Koh and Henri Justino, M.D., of Texas Children’s and Baylor; biomedical engineer Balakrishna Haridas, Ph.D., of Texas A&M University; bioengineer Maria Oden, Ph.D., of Rice University; and Michael Heffernan, Ph.D., also a bioengineer, of Fannin Innovation Studio in Houston.
Justino, director of the Charles E. Mullins Cardiac Catheterization Laboratories at Texas Children’s, was recently part of the TMC Innovation Institute’s TMCx medical device accelerator program with his company, Polyvascular, which creates tiny replacement heart valves for treating pediatric congenital heart disease.
RELATED STORY: Tiny Valves for Tiny Bodies
Koh said TMC Innovation, and its programs including TMCx, Johnson & Johnson Innovation’s JLABS @ TMC, and J&J’s Center for Device Innovation, will play a role in this initiative as well.
“This is really a collaborative effort across the Texas Medical Center to help accelerate the products,” Koh said. “We are basically going to serve as navigators to help pediatric innovators get the right expertise so they are able to go all the way from an idea to commercialization—what we call the total product life cycle.”
Veterans use art to help others during their recovery https://t.co/vcMbVOHCEY via @NY1
Managing an overactive bladder can be difficult while traveling for summer vacation. Dr. Alexander Pastuszak shares some tips on what you can do to travel more comfortably. https://t.co/0vIlkV3nlV #overactivebladder #traveltips
In observance of Men’s Health Month, the experts at UTHealth and @UTPhysicians the clinical practice of @McGovernMed, have identified five things men need to know to keep their health in check: https://t.co/i7EIgZOhWM
Camp For All 2U brings summer camp to Texas Children's Hospital! Patients are invited to go canoeing, participate in archery and make new friends. Learn more from @HoustonChron : https://t.co/k1slUCnqAn
Let’s talk about the Big Four. And we’re not referencing the number of major American pro sports leagues, gentlemen. Read more: https://t.co/INqCdH6RTT. #menshealthmonth https://t.co/iPcveD89NP
Q&A: @SecWilkie on VA Mission Act https://t.co/lEsiraS6o4 via @wvpublic
TAMU Health Sciences@TAMHSC
Today we opened our brand new research facility! The Medical Research and Education Building II doubles the existing research space for the Health Science Center on the Bryan campus. Whoop! 👍Learn more about the MREB II → https://t.co/DtcNt2hlLY https://t.co/slDVZDeXXF
Our @DavidHongMD explains how tisotumab vedotin works in treating #cervicalcancer: https://t.co/xebLn7m3cI @OncLive #gynsm #endcancer
University of Houston@UHouston
RT @UHOnlineCoogs: The B.A and B.S in Psychology is offered online. These completion degrees are for students who have some college credit…
CHI St. Luke's Health@CHI_StLukes
RT @KHOU: Get well soon, Mack! https://t.co/WDk43ZutWp
Want to donate goods or services to MD Anderson to support our patients? Learn about what items can be donated: https://t.co/5HsnmWmxdt #endcancer
University of Houston@UHouston
RT @UHadmissions: Another week means another #TributeTuesday! Christine Ha, @theblindcook won the @MASTERCHEFonFOX competition, and is also…
@vigilcd @JLo We're thinking of you, Camille. Let us know if you need anything while you're here.
Today marks the 69-year anniversary of the #KoreanWar, which began on June 25, 1950.We thank all #Veterans who served during this conflict and honor their sacrifice.#HonoringVets https://t.co/r8vw723Mxg
RT @Daily_Experts: Congratulations to Dr. Tetsuo Ashizawa of Houston Methodist Hospital -- Recognized as an Expertscape World Expert in Ata…